Structure Analysis of Tamsulosin Hydrochloride
- VernacularTitle:盐酸坦索罗辛结构解析
- Author:
Lin LUO
- Publication Type:Journal Article
- Keywords:
Tamsulosin hydrochloride;
Magnetic resonance;
Structure analysis
- From:
China Pharmacy
2005;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the structure of tamsulosin hydrochloride by spectral data.METHODS:The spectra of 1H NMR,DEPT,13C NMR,1H-1HCOSY,HMQC、HMBC,MS,FT-IR and UV of tamsulosin hydrochloride were determined and interpreted.RESULTS:All the 1H NMR and 13C NMR chemical shifts were assigned rationally.The peaks of functional group vibrations(FT-IR),the main fragment peaks(MS)and UV characteristic absorption were all explained reasonably.CONCLUSION:The above analytical data of all kinds of spectra coincided with the structure of tamsulosin hydrochloride.