Adverse Drug Reaction Induced by Cemetidine:Literature Analysis of 306 Cases
- VernacularTitle:306例西咪替丁不良反应文献分析
- Author:
Li WANG
;
Ting XU
;
Yao TANG
- Publication Type:Journal Article
- Keywords:
Cimetidine;
ADR;
Literature analysis
- From:
China Pharmacy
2005;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the general pattern and characteristics of adverse drug reactions (ADR) induced by cimetidine. METHODS: A total of 306 ADR cases induced by cimetidine reported by domestic journals of 1983～2007 were analyzed statistically. RESULTS: The clinical manifestations of ADR induced by cimetidine were complicated and various and characterized by lesions of central nervous system (27.78%), cardiovascular system (21.24%), endocrine disturbance (8.82%) and hematological system (8.82%) etc. CONCLUSION: Great importance should be attached to the ADR induced by cimetidine to guard against the serious ADR such as aplastic anemia, cardiac arrest and allergic shock.
