The Effect of Helicobacter Pylori Eradication on Atrophy of Gastric Antrum Mucosa and Intestinal Epithelium Mucosae Metaplasia
- VernacularTitle:根除幽门螺杆菌对胃窦部黏膜萎缩和肠上皮化生的影响
- Author:
Ping YAO
;
Qunying WANG
;
Zengwen FENG
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Gastric;
Atrophy;
Intestinal metaplasia
- From:
Chinese Journal of Prevention and Control of Chronic Diseases
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathological changes of gastric antrum mucosa after Helicobacter pylori eradication.Methods Total 180 cases who suffered from epigastralgia and took the endoscopic examination were randomly divided into two groups,one was Hp eradication group which included 98 cases and given anti-Hp medication treatment,and the other was control group which included 82 cases and given an expectant treatment.At the end of the study,they took reexamination by gastroscope and tests on Hp by Giemsa dyeing & rapid urase detection and on gastric antrum pathological changes by HE dyeing.Results In treatment group,atrophic gastritis as well as intestinal metaplasia decreased significantly after Helicobacter pylori eradication,but in control group,no change of atrophic gastritis was found while intestinal metaplasia aggravated.Conclusion The eradication of Helicobacter pylori is able to decrease atrophic gastritis and intestinal metaplasia.
