Clinical Efficacy of Reduced Glutathione in Combination with Polyene Phosphatidylcholine for Non-alcoholic Fatty Liver Disease
- VernacularTitle:还原型谷胱甘肽联合多烯磷脂酰胆碱治疗非酒精性脂肪性肝病的疗效观察
- Author:
Qijie ZHANG
- Publication Type:Journal Article
- Keywords:
Polyene Phosphatidylcholine;
Reduced glutathione;
Non-alcoholic fatty liver disease
- From:
China Pharmacy
2005;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical efficacy of reduced glutathione combined with Polyene Phosphatidylcholine for non-alcoholic fatty liver disease. METHODS: 60 patients with non-alcoholic fatty liver disease were randomly divided into trial group and control group: 30 patients in trial group were infused iv gtt with Polyene Phosphatidylcholine (10 mL) and reduced glutathione (1 200 mg) once daily for 1 months,and 30 in control group with Polyene Phosphatidylcholine (10 mL) once daily for 1 months. Parameters of liver function and blood lipid and color ultrasonic examination of two groups before and after treatment were compared for evaluation of therapeutic effects. RESULTS: In respect of the reduction of alanine aminotransferase (ALT),aspartate aminotransferase (AST) and ?-GT,there were significant differences between the trial group and the control group in the effective rate (90.0% in trial group versus 63.3 % in control group,P0.05). CONCLUSION: Used concomitantly,reduced glutathione and Polyene Phosphatidylcholine showed satisfactory efficacy for non-alcoholic fatty liver disease.
