Function of Shh gene in the development of embryos
- VernacularTitle:Shh基因在胚胎发育过程中的调控作用
- Author:
Yunan ZHOU
;
Bo HU
- Publication Type:Journal Article
- Keywords:
Genes,Shh;
Transcription factor Gli;
Fetal development
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Mammals have three genes with homology to the hh gene.These comprise Sonic hedgehog(Shh),Indian hedgehog(Ihh),and Desert hedgehog(Dhh).Shh has been shown to play a crucial role in embryogenesis and the development of ectoderm.Shh has the great relationship with the forming all the system.Shh-Patched-Smoothened signal pathway will lead the embryogenesis in the normal way.Otherwise,the abnormal embryogenesis,malformation,and tumor will be happened.
