Determination of Gastrodin in Shulenaoxintong Granules by HPLC
- VernacularTitle:HPLC法测定舒乐脑心通颗粒中天麻素的含量
- Author:
Guangsheng LI
- Publication Type:Journal Article
- Keywords:
Gastrodin;
Shulenaoxintong granules;
HPLC;
Content determination
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish an HPLC method for the determination of Gastrodine in Shulenaoxintong granules. METHODS: The chromatographic column was Hypersil ODS(250 mm?4.0 mm,5 ?m) with a mobile phase consisted of acetonitrile-0.05%phosphorin acid(2∶98) at a flow rate of 1 mL?min-1. The detective wavelength was set at 220 nm. RESULTS: A good linearity was obtained in the range of 0.1～2.0 ?g(r=1.000 0), and the average recovery was 96.6% (RSD=0.80%,n=6). CONCLUSION: The method is convenient, rapid, and reproducible, and it is applicable for the qua-lity control of Shulenaoxintong granules.
