Five Angiotensin Converting Enzyme Inhibitors for Essential Hypertension:Cost-Effectiveness Analysis
- VernacularTitle:血管紧张素转换酶抑制剂类药物治疗原发性高血压的成本-效果分析
- Author:
Jiawei WANG
;
Cheng ZHANG
- Publication Type:Journal Article
- Keywords:
Essential hypertension;
Captopril;
Fosinopril;
Benazepril;
Enalapril;
Cost-effectiveness analysis
- From:
China Pharmacy
2005;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the cost-effectiveness of 5 angiotensin converting enzyme inhibitors in the treatment of essential hypertension.METHODS:120 patients with essential hypertension were randomly assigned to receive domestic captopril(Group A),captopril from joint venture(Group B),fosinopril(Group C),benazepril(Group D)or enalapril(Group E)for 4 weeks.The cost-effectiveness of the 5 groups was evaluated.RESULTS:The total effective rates for A,B,C,D and E groups were 75.00%,75.00%,91.67%,91.67% and 87.50%,respectively.As compared with Group A,the incremental cost-effectiveness ratios of C,D and E groups were 1 249.67,1 256.39 and 636.16,respectively.CONCLUSION:The total effective rate in Group E is slightly less than in other groups,yet Group E is superior to other groups because of its lower cost-effectiveness ratio and lower incremental cost-effectiveness ratio.
