Preparation and Content Determination of Lincomycin Hydrochloride Glycerol Paint
- VernacularTitle:盐酸林可霉素甘油涂剂的制备及含量测定
- Author:
Hanlin LIU
;
Ping HU
;
Jiafu ZHOU
- Publication Type:Journal Article
- Keywords:
Lincomycin hydrochloride glycerol paint;
Preparation;
Content determination;
HPLC
- From:
China Pharmacy
2005;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To prepare lincomycin hydrochloride glycerol paint and to determine its content. METHODS: Lincomycin hydrochloride glycerol paint was prepared using lincomycin hydrochloride and dyclonine hydrochlorideas as main components; the contents of the two main components were determined by HPLC. RESULTS: The linear ranges of lincomycin hydrochloride and dyclonine hydrochloride were 20～200 ?g?mL-1(r=0.999 8) and 10～100 ?g?mL-1(r=0.999 9),respectively. The average recoveries(n=5) were 99.61% and 99.28%,with RSD stood at 0.439% and 0.818%,respectively. CONCLUSION: Both the preparative method and determination method for lincomycin hydrochloride glycerol paint are simple and feasible.
