Preparation and Curative Effects of Different Compound Scald Preparations for Deep Ⅱ? Scald
- VernacularTitle:不同复方烫伤制剂的制备及其对兔深Ⅱ?烫伤的修复作用研究
- Author:
Yan TIAN
;
Ge TIAN
- Publication Type:Journal Article
- Keywords:
Gels;
Ointments;
Film agent;
Deep Ⅱ? scald model;
Repairing effect
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare different compound scald preparations and to investigate their repairing effects for deep Ⅱ? scald in rabbits.METHODS:The deep Ⅱ? scald model was established in depilated rabbits by infrared radiation.Then the rabbits in the trial groups were treated with the same drug at different dosage and different forms of medication:compound scalded gels,compound scalded ointments and the compound scalded films,with Moist Exposed Burn Ointment as positive control and 0.9% NaCl aqueous solutions blank.After a certain time of treatment,the contraction of the scald skin was observed and the average value of the diameter of the scald skin was calculated.RESULTS:In three trial groups and Moist Exposed Burn Ointment positive control group,no scald infection occurred,and the healing surfaces of the scalds were all smooth and even.However,the healing time was different between 3 trial groups and Moist Exposed Burn Ointment positive control group,with compound scalded gels showing the best efficacy in that the scald surfaces were free from infection,the healing surfaces were smooth and even,and the contracted diameter of the scalded skin was significantly lower than in other groups,showing significant differences as compared with other groups(P
