Detection of paraquat in biological tissues by LC/MS/MS
- VernacularTitle:LC/MS/MS法测定生物组织中百草枯
- Author:
Zhaohong WANG
;
Zhong WANG
;
Xuejun LIU
- Publication Type:Journal Article
- Keywords:
Forensic toxicologcal analysis;
Paraquat;
Solid phase extraction;
LC/MS/MS
- From:
Chinese Journal of Forensic Medicine
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective A LC/MS/MS method is developed for determination of paraquat in biological tissue.Methods The samples were pretreated with solid phase extraction using Oasis WCX cartridges and separated with HPLC,paraquat could be identified by LC/MS/MS.Result Calibration curves were linear on injection of amounts ranging from 0.02~20?g/ml and the limit of detection was 10ng/ml(S/N≥3).Conclusion The described menthod was proved to be sensitive,rapid and accurate,it will be applied in identification and determination of paraquat in biological tissues.