Ramipril/Atorvastatin for Diabetic Nephropathy:Clinical Observation
- VernacularTitle:雷米普利与阿托伐他汀单用或联用治疗糖尿病肾病临床观察
- Author:
Yaohui ZHOU
;
Ling XU
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathy;
Ramipril;
Atorvastatin
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To observe the renal protective effects of ramipril and atorvastatin used in combination or alone for diabetic nephropathy. METHODS: 54 patients were randomly assigned to receive ramipril 5 mg q.d (Group A), atorvastatin 10 mg q.d (Group B) or ramipri 5mg qd + atorvastatin 10mg q.d (Group C) for 18wk. RESULTS: After 18-week treatment, levels of both urine protein and blood lipid decreased in all the three groups (P0.05). CONCLUSION: Either Ramipril or Atorvastatin alone had satisfactory effect on diabetic neph-ropathy, but a more remarkable protection effect on kidney was noted when they used in combination.