Omeprazole-induced ADR:Literature Analysis of 96 Cases
- VernacularTitle:奥美拉唑致不良反应96例文献分析
- Author:
Yingchun XIANG
- Publication Type:Journal Article
- Keywords:
Omeprazole;
ADR;
Literature analysis
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the condition and the related factors of adverse drug reactions (ADR) occurred in our hospital. METHODS: A total of 75 omeprazole-induced ADR reports (96 cases) retrieved from 1996 to Mar. 2007 published in domestic medical journals were analyzed statistically. RESULTS: Omeprazole-induced ADR were mostly seen in males aged from 41 to 60, but which was independent of sex. The ADR induced by oral administration usually appeared within 3 days to 2 weeks, while those induced by injection were more often seen at 3～5 min or 3 days later. The ADR might involve multi-organs or systems, and their clinical manifestations were various and complicated, chiefly characterized by allergic reactions and hypolekocytosis, or even allergic shock in severe cases. CONCLUSION: ADR induced by omeprazole call for great attention in the clinic.
