Identification Method of Four Chemicals in Antiasthmatic and Antitussive Chinese Patent Medicine
- VernacularTitle:平喘镇咳类中成药中非法添加4种化学药品检验方法的研究
- Author:
Li LI
;
Gangping ZHANG
;
Xiaomin LI
;
Xueyan BI
;
Zuolian ZHAO
;
Zhigang WANG
- Publication Type:Journal Article
- Keywords:
Antiasthmatic and antitussive;
Chinese patent medicine;
Chemicals;
HPLC;
Identification method
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for the identification of four chemicals-Ephedrina Hydrochloridum,prednisone acetate,codeine phosphate and dexamethasone acetate in antiasthmatic and antitussive Chinese patent medicine.METHODS:With Kening capsule(an antitussive) as positive control,the chemicals which were illegally added into the antiasthmatic and antitussive Chinese patent medicine were determined by HPLC with octadecylsilane chemically bonded silica as loading agent.RESULTS:Under the same chromatographic condition,the four chemicals could all be detected.CONCLUSION:The method is simple,practical and specific,and it can be applied to detect the illegally added chemicals in antiasthmatic and antitussive Chinese patent medicine.