Tacrolimus plus Mycophenolate Mofetil(MMF) for Patients with Chronic Allograft Dysfunction
- VernacularTitle:他克莫司联合吗替麦考酚酯用于慢性移植肾功能减退患者的临床疗效观察
- Author:
Li WANG
;
Yiping LU
;
Jia WANG
;
Keshi TANG
- Publication Type:Journal Article
- Keywords:
Tacrolimus;
Mycophenolate mofetil;
Chronic allograft dysfunction(CAD)
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To discuss our experience of switching use of immunosuppressive agents for patients after renal transplantation.METHODS:23 patients with chronic allograft dysfunction(CAD) were treated with tacrolimus + mycophenolate mofetil instead of cyclosporine A+ azathioprine.The change of renal function and the adverse effects were observed.RESULTS:The serum creatinine(Scr) level before and after therapy conversion were 167～478 ?mol?mL-1 with a mean value of(268?78) ?mol?mL-1 and 112～346 ?mol?mL-1 with a mean value of(174?65) ?mol?mL-1,respectively,showing significant difference in the t test(P
