Adverse Reactions Caused by Main Antituberculosis Drugs:Literature Analysis of 409 Cases
- VernacularTitle:409例主要抗结核药不良反应文献分析
- Author:
Qi LI
;
Ying SUN
;
Yaqian DUAN
- Publication Type:Journal Article
- Keywords:
Antituberculosis drug;
Adverse drug reaction;
Literature analysis
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the characteristics of adverse drug reactions(ADR) induced by antituberculosis drugs so as to provide references for the rational use of drugs in the clinic.METHODS:409 ADR cases induced by 5 main antituberculosis drugs in domestic medical journal from Jan.1997 to Dec.2006 were collected and analyzed statistically.RESULTS:Many systems were involved in ADR,such as skin,urinary system,neural system,hematological system,etc.,which were associated with allergic reaction and toxicity of drugs.Acute renal failure(ARF),drug eruption,fever and anaphylactic shock showed high incidences.CONCLUSION:Attention should be paid to ADR induced by antituberculosis drugs to standardize treatment.
