Effect of Zaohuang Capsule No.3 on the Human Glomerular Mesangial Cells
- VernacularTitle:藻黄胶囊Ⅲ号对人肾小球系膜细胞的影响
- Author:
Jianwei JU
;
Shoubo BO
;
Bin SHANG
- Publication Type:Journal Article
- Keywords:
Zaohuang Capsule No.3 (Capsule of Sargassum and Radix et Rhizoma Rhei);
Glomerular mesangial cell;
Fibronectin (FN);
Interleukin-6;
Transforming growth factor ?1 (TGF-?1)
- From:Journal of Traditional Chinese Medicine
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the molecular and cellular mechanism of Zaohuang Capsule No.3 (ZHC3) in treating chronic renal failure through observing the effect of ZHC3 on the human glomerular mesangial cells (GMC). Methods The proliferation of human GMC fostered in ZHC3 was detected by MTT, and the fibronectin (FN), interleukin 6 (IL-6) and transforming growth factor ?1 (TGF-?1) secretion was detected by ELISA. Results ZHC3 significantly inhibited GMC proliferation (P
