Effect of hypoxia on chemotaxis of rat polymorphonuclear leukocytes
- VernacularTitle:缺氧对大鼠中性粒细胞趋化能力的影响
- Author:
Gang ZHANG
;
Yuqi GAO
- Publication Type:Journal Article
- Keywords:
Hypoxia;
Chemotaxis;
Neutrophils
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the effect of acute and chronic hypoxia on the chemotaxis of polymorphonuclear leukocytes(PMNs) of rats.METHODS: Serum and PMNs were separated from rats under normoxia, acute hypoxia and chronic hypoxia condition,and cell aspiration technology system was used to determine the chemotactic migration of pseudopod of PMNs induced by serum as chemotactic factor.RESULTS: Induced by autoserum,the length of pseudopod of PMNs migrated into micropipette [(1.200?0.178)?m,(1.094?0.164)?m ]under acute hypoxic and chronic hypoxic condition was significantly longer than the corresponding value for control[(0.914?0.156)?m,P
