Preparation Technology of Gross Saponins Tribullu Terrestris Dropping Pill
- VernacularTitle:蒺藜皂苷滴丸成型工艺的研究
- Author:
Ji ZHANG
;
Chunlin YAN
;
Danshen ZHANG
;
Jingjuan ZHI
;
Guiping XUE
- Publication Type:Journal Article
- Keywords:
Gross Sasponins Tribullu terrestis droping pill;
Orthogonal test;
Study on preparation technology
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the best preparation technology of Gross Saponins tribullu terrestris droping pill. METHODS: The ratio of Gross Spongines Tribullu terrestris to matrix, dripping temperature, dripping distance and dripping speed were investigated by preliminary test and orthogonal test with sphericity, the variation coefficient of weight of pill,time limit of dissolution and appearance of the dropping pill were taken as scoring indexes. Meanwhile, the technical conditions were optimized by orthogonal test on the basis of preliminary test.RESULTS: The optimal technical conditions were as follows: the ratio of matrix to Gross Saponins Tribullu terrestris was 5∶1;the dripping temperature was 85 ℃;the dripping speed was 8 d?min-1 and the dripping distance was 12 cm.CONCLUSION:The technology is simple, feasible and the evaluation indexes were reliable and reasonable and it can meet the requirement for dripping pill specified in China Pharmacopeia (2005 Edition).
