Experimental studies on time TIMP-1 and a-ACTIN of injuried heart caused by electric current
- VernacularTitle:电击伤后大鼠心肌TIMP-1表达的实验研究
- Author:
Shouting PAN
;
Lihua WAN
;
Jianping BU
- Publication Type:Journal Article
- Keywords:
Forensic pathology;
Electric injury;
TIMP-1;
Injury time
- From:
Chinese Journal of Forensic Medicine
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the temporal expressions of TIMP-1 and their relationship with injury time during electric injuris of hearts of rats.Methods Immunohistorichemical and image-analysis techniques were employed in 220V-electric injury of hearts during different time.ResultsWeak expression of TIMP-1 are deteced at 0.5h after electric injury,which increased subsequently,and peaked at 24~72h post-injury.Then decreased to pre-injury level at 12d.Conclusion The time-dependent expression of TIMP-1 during electric injury may be used for the estimation of injury time.