Effect of Huangqi Injectio on Abnormal Expression of Aquaporin-1 Caused by Glucose Lactate Peritoneal Dialysis Solution

VernacularTitle:黄芪注射液对含糖乳酸盐腹膜透析液所致水孔蛋白1表达异常的影响
Author: Yi WANG ; Jing SHU ; Weihua HU
Publication Type:Journal Article
Keywords: Huangqi (Radix Astragali seu Hedysari) Injectio; Peritoneal dialysis; Aquaporin-1
From: Journal of Traditional Chinese Medicine 1993;0(02):-
CountryChina
Language:Chinese
Abstract: Objective To observe the effect of Huangqi (Radix Astragali seu Hedysari) Injectio on the abnormal expression of aquaporin-1 (AQP-1) caused by glucose lactate peritoneal dialysis solution. Methods Different glucose concentration lactate peritoneal dialysis solutions and Huangqi Injectio given to the rats intraperitoneally. Eight weeks later, the ultrafiltration of peritoneal dialysis, peritoneum clearance, peritoneal structure, AQP-1 and its gene expression were observed. Results Compared with the control group, in the glucose and Huangqi groups, the ultrafiltration of peritoneal dialysis was remarkably decreased (P