Preparation and Quality Control of Dexamethasone Acetate Borneol Cream
- VernacularTitle:醋酸地塞米松冰片霜的制备及质量控制
- Author:
Renfa JIANG
;
Ning TAO
;
Chang YU
;
Ke LI
;
Haode FENG
- Publication Type:Journal Article
- Keywords:
Dexamethasone acetate borneol cream;
TLC;
Ultraviolet spectrophotometry;
Preparation;
Quality control
- From:
China Pharmacy
1991;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare dexamethasone acetate borneol cream and to establish its quality control method.METHODS:Dexamethasone acetate borneol cream was prepared by grinding method;dexamethasone acetate and phenol were identified by TLC,and the content of the principal agent was determined by ultraviolet spectrophotometry.RESULTS:The prepared cream fitted the description of China Pharmacopeia(2005 edition) in identification and tests etc.The linear range of dexamethasone acetate was 12.06～28.14 ?g?mL-1(r=0.999 7),and the average recovery rate of 98.52%(RSD=0.66%).CONCLUSION:The preparation is reasonable in compounding,simple and feasible in techniques,and its quality is stable and controllable.
