Study the Effects of Herba Siegesbeckiae Capsule on Cerebral Blood Flow and Cerebral Vessel Resistance in Anesthetized Dogs
- VernacularTitle:豨莶草胶囊对麻醉犬脑血流量及脑血管阻力影响的研究
- Author:
Yingmei FU
;
Guangren LIAO
- Publication Type:Journal Article
- Keywords:
Herba Siegesbeckiae capsule;
Cerebral blood flow;
Cerebral vessel resistance;
Empirical study
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the effect of Herba Siegesbeckiae capsule on cerebral blood flow (CBF), cerebral vessel resistance (CVR), blood pressure (BP), electrocardiogram (ECG) and heart rate (HR)in anesthetized dogs. METHODS: The external carotid arteries on one side and the vertebral arteries of dogs were ligated, then the CBF of carotid arteries was measured by electromagnetic flowmeter, and the BP, EGG and HR were measured by polygraph. RESULTS: Herba Siegesbeckiae capusle could significantly increase CBF and decrease CVR; however, it has no effect on BP, ECG and HR. CONCLUSION: Herba Siegesbeckiae capsule can improve cerebral blood circulation through increasing CBF and decreasing CVR.
