Quality Criteria of Kesuting Oral Liquid
- VernacularTitle:咳速停口服液质量标准研究
- Author:
Lili BAI
;
Xinan WU
;
Gang ZHAO
- Publication Type:Journal Article
- Keywords:
Kesuting oral liquid;
TLC;
HPLC;
Quality criteria
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the quality criteria of Kesuting oral liquid. METHODS: Qualitative identification of Herba Ephedrae,Folium Mori and Radix Et Rhizoma Glycyrrhizae was conducted using TLC method. The content of Baicalin was determined by HPLC in which the chromatographic separation was performed on Spherigel ODS C18(250mm?4.6mm,5?m) column with mobile phase consisted of methanol-0.4%phosphate solvent(52∶48) at a flow rate of 1.0 mL?min-1. The UV wavelength was set at 280 nm. RESULTS: The TLC spots of Herba Ephedrae,Folium Mori and Radix Et Rhizoma Glycyrrhizae were characteristic and obvious, and which can be used for qualitative identification. The linear range of Baicalin was 0.24～1.20 ?g (r=0.999 8) with a mean recovery rate of 98.72%(RSD=1.02%,n=6). CONCLUSION:The establish criteria are suitable for the quality control of Kesuting oral liquid.
