Expression and correlation of COX-2 and VEGF-C in nasopharyngeal carcinoma
- VernacularTitle:鼻咽癌组织中环氧化酶2和血管内皮生长因子C的相关性
- Author:
Hong YUAN
;
Haiming WEI
;
Jianping LIANG
;
Jinlong LU
;
Tao WANG
- Publication Type:Journal Article
- Keywords:
Nasopharyngeal Neoplasms;
Cyclooxy-genase 2;
Vascular Endothelial Growth Factor C;
Immunohistochemistry
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate vascular endothelial growth factor-C (VEGF-C) and cyclooxyegense-2(COX-2) expression in nasopharyngeal carcinoma. METHODS The expression of COX-2 and VEGF-C were stained respectively in nasopharyngeal carcinoma tissues of 45 patients using immunohistochemical method,and were analyzed with clinical data. RESULTS The positive expression rates of COX-2 and VEGF-C were 68.9 % and 53.3 % respectively in nasopharyngeal carcinoma tissue. The expression of COX-2 was positively correlated with VEGF-C (r=0.334,P
