Assaying of Metformin in Compound Rosiglitazone Metformin Tablet by UV Spectrophotometry
- VernacularTitle:紫外分光光度法测定复方罗格列酮二甲双胍片中盐酸二甲双胍的含量
- Author:
Guojun WANG
- Publication Type:Journal Article
- Keywords:
UV spectrophotometry;
Compound rosiglitazone metformin tablet;
Metformin;
Content
- From:
China Pharmacy
1991;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To develop a method for the assaying of metformin in compound rosiglitazone metformin tablet.METHODS:The determination was performed at a wavelength of 233 nm.The absorbability was detected with metformin as control and its content was computed.RESULTS:The linear range of metformin was 1.242～11.18 ?g?mL-1(r=0.999 9) and its average recovery was 100.04%(RSD=0.22%).CONCLUSION:The method is simple,rapid,and accurate,and suitable for the quality control of compound rosiglitazone metformin tablet.
