Drug-induced Hepatic Lesions:Clinical Analysis of 170 Cases
- VernacularTitle:170例药物性肝损害的临床分析
- Author:
Jianxia DU
;
Ling SHEN
- Publication Type:Journal Article
- Keywords:
Drug-induced hepatic lesions;
Retrospective analysis;
Clinical feature
- From:
China Pharmacy
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To discuss the clinical features and the general pattern of drug-induced hepatic lesions.METHO-DS:The clinical data of 170 drug-induced hepatic lesion cases collected from Jan.2002 to Apr.2006 in our hospital were analyzed retrospectively.RESULTS:Of the 170 cases,35.29% were induced by Chinese herbal medicines,13.53% by antipsychotic drugs,12.94% by anti-tuberculosis agent;51.18% were hepatocellular damage type,14.12% cholestatic damage type and 34.71% damage of mixed type damage.CONCLUSION:Hepatic lesions resemble viral hepatitis and were of no specificity in clinical features;various drugs can lead to hepatic lesions and to which clinic should attach great importance.
