Three Cases of Amyloidosis Diagnosed by Endoscopic Biopsy of Stomach.
- Author:
Han Min LEE
1
;
Yun Jung KIM
;
Cheol EOM
;
Sang Don KIM
;
Suk Bae JI
;
Kwang Je LEE
;
Jin Hong KIM
;
Seong Won JO
;
Hyun Lee YIM
Author Information
1. Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea.
- Publication Type:Case Report
- Keywords:
Erosive gastritis;
Gastric amyloidosis
- MeSH:
Amyloidosis*;
Anorexia;
Arthritis, Rheumatoid;
Biopsy*;
Colchicine;
Deglutition Disorders;
Diagnosis;
Diarrhea;
Drug Therapy;
Gastritis;
Heart;
Humans;
Intestinal Obstruction;
Kidney;
Multiple Myeloma;
Nausea;
Peritoneal Dialysis;
Plaque, Amyloid;
Stomach*;
Ulcer;
Ventilators, Mechanical;
Vomiting
- From:Korean Journal of Gastrointestinal Endoscopy
1998;18(3):359-367
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Since amyloidosis is usually diagnosed later in the disease process, a high index of suspicion is therefore necessary for earlier diagnosis. Confirmative diagnosis rests on a biopsy of the involved organ. Gastrointestinal amyloidosis causes a variety of symptoms including intestinal obstruction, ulcers, malabsorption, hemorrhaging, protein loss, diarrhea, anorexia, nausea, vomiting, and dysphagia. We confirmed amyloid deposits in the stomach in three patients with epigastric pain through a biopsy of erosive gastritis documented on a gastrofiberscopy. One patient with primary amyloidosis which had invaded his kidney, stomach, and heart, expired, although aggressive treatment with a pacemaker insertion, peritoneal dialysis, and ventilator care was performed. Another patient with multiple myeloma died on the 38th day, after having started systemic chemotherapy. The other patient with secondary amyloidosis due to rheumatoid arthritis, is currently receiving colchicine at our out patient clinic.