Compatible Stability of Gatifloxacin for Injection with Etamsylate Injection
- VernacularTitle:注射用加替沙星与酚磺乙胺注射液的配伍稳定性考察
- Author:
Jizhang YANG
;
Zengren ZHAO
;
Ruiqin LIU
;
Shumin YANG
- Publication Type:Journal Article
- Keywords:
Gatifloxacin for injection;
Etamsylate injection;
Compatible;
Stability;
UV Spectrophotometry
- From:
China Pharmacy
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the compatibility of gatifloxacin for injection with etamsylate injection in 0.9% sodium chloride injection and 5% glucose injection.METHODS:The appearance of the mixture of gatifloxacin for injection with etams-ylate injection in 0.9% sodium chloride injection and 5% glucose injection at room temperature,i.e.(20?1)℃ within 8 hours was observed,with its pH measured and ultraviolet spectra observed.The contents of gatifloxacin and etamsylate were determined by a dual ultraviolet spectrophotometry.RESULTS:No significant change was noted for the mixture within 8 h in pH and appearance,and the contents of gatifloxacin and etamsylate within 8 h in 0.9% sodium chloride injection or within 6 h in 5% glucose injection showed no obvious change.CONCLUSION:Gatifloxacin for injection can be mixed with etamsylate injection in 0.9% sodium chloride injection or 5% glucose injection.
