Prevention and Treatment of Chronic Pyelonephritis with Yishenkang Granule:Clinical Immunology Study
- VernacularTitle:益肾康颗粒防治慢性肾盂肾炎的临床免疫学研究
- Author:
Lianhua LI
;
Shiping CHENG
- Publication Type:Journal Article
- Keywords:
Chronic pyelonephritis;
Yishenkang granule;
Immune function
- From:
China Pharmacy
2005;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the links between chronic pyelonephritis (CPN) and immune function, and the action mechanism of Yishenkang granule on CPN. METHODS: A total of 120 CPN cases were randomly assigned to Yishenkang granule group, Sanjing tablet group and western medicine group, which were compared with healthy control group. The levels of the peripheral blood T lymphocyte subsets, serum immunoglobulin, complement, secretory IgA in urine and the cell factor IL-2 in CPN cases before and after treatment were detected by monoclonal antibody method, agar diffusion method, radioimmunoassay, radioimmune balancing method and compared with those in healthy control group. RESULTS: In CPN cases compared with healthy control group, the levels of serum immunoglobulin, complement, secretory IgA in urine were significantly lower while the level of cell factor IL-2 were significnatly higher (P