A Case of Cytomegalovirus Duodenitis Following an Allogenic Bone Marrow Transplantation.
- Author:
Jin Hee AHN
1
;
Hwoon Yong JUNG
;
Je Hwan LEE
;
Yang Soo KIM
;
Kyoo Hyung LEE
;
On Ja KIM
;
Woo Kun KIM
;
Sang Hee KIM
;
Weon Seon HONG
;
Young Il MIN
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Cytomegalovirus;
Bone marrow transplantation;
Duodenitis
- MeSH:
Adult;
Bone Marrow Transplantation*;
Bone Marrow*;
Cytomegalovirus*;
Diagnosis;
Duodenitis*;
Endoscopy;
Ganciclovir;
Gastrointestinal Tract;
Humans;
Immunocompromised Host;
Male;
Mortality;
Mucous Membrane;
Nausea;
Vomiting
- From:Korean Journal of Gastrointestinal Endoscopy
1998;18(3):392-397
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytomegalovirus(CMV) disease is one of the major causes of morbidity and mortality in immunocompromised patients, such as recipients of a solid organ or bone marrow allo-graft and patients with acquired immnune deficiency syndrome, CMV infection of the gastrointestinal tract may vary in location, extent, and clinical manifestation. As there is no pathognamonic endoscopic feature for CMV disease, a diagnosis of CMV infection has been made by confirming cytomegalic cells in mucosal specimens obtained from the gastrointestinal tract by an endoscopy. We repcet a case of a 38-year-old male patient with CMV duodenitis following an allogenic bone marrow transplantation(BMT), who had prolonged nausea and vomiting for 5 weeks after the BMT. He was diagnosed as having CMV duodenitis by identifying cytomegalic cells in duodenal mucosa biopsied by endoscopy and recovered after the treatment of ganciclovir.