On Quality Criteria of Bushenqiangshen Capsule
- VernacularTitle:补肾强身胶囊质量标准研究
- Author:
Ting MENG
- Publication Type:Journal Article
- Keywords:
Bushenqiangshen capsule;
TLC;
HPLC;
Icariin;
Quality criteria
- From:
China Pharmacy
2007;0(36):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish quality criteria for Bushenqiangshen capsule. METHODS:TLC was employed to identify Herba Epimedii and Fructus Ligustri Lucidi. HPLC was applied for the determination of content of Icariin. The chromatographic separation was performed on octadecylsilane chemically bonded silica packed column (250mm?4.6mm,5?m). The mobile phase was composed of acetonitrile and methyl alcohol (30∶70) at a flow rate of 1.0mL?min-1. The detection wavelength was 270nm and the column temperature was 30℃. RESULTS:Herba Epimedii and Fructus Ligustri Lucidi were well-separated and clear spots were noted in their TLC. The linear range of icariin was 0.266 4～0.932 4?g (r=0.999 9,n=6), and the average recoveries was 99.77%(RSD=1.89%). CONCLUSION:The established criteria can be used for the quality control of Bushenqiangshen capsules.
