Clinical Observation about Urokinase vs.Low Molecular Weight Heparin for Acute Pulmonary Thromboembolism
- VernacularTitle:尿激酶与低分子肝素治疗急性肺血栓栓塞症的临床观察
- Author:
Yanmin YAO
;
Xizhu WANG
;
Qiaofeng SONG
;
Chunrong LIU
;
Yiping HAN
- Publication Type:Journal Article
- Keywords:
Urokinase;
Low molecular weight heparin;
Acute pulmonary thromboembolism;
Thrombolysis;
Anticoagulation
- From:
China Pharmacy
2007;0(35):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the efficacy of Urokinase vs.Low Molecular Weight Heparin in the treatment of acute pulmonary thromboembolism.METHODS:A total of 35 patients with acute pulmonary thromboembolism who had no past history of heart and lung diseases were enrolled and randomly assigned to two groups following ultrasonography and pulmonary ventilation/perfusion scanning:15 were given thrombolysis therapy with urokinase,and 20 given anticoagulation therapy with low molecular weight heparin.Symptoms,arterial blood gas analysis,electrocardiogram,echocardiogram were compared in two groups before and after treatment.RESULTS:The patients receiving thrombolysis therapy had better improvement in symptoms,arterial blood gas index,echocardiogram and the pulmonary ventilation/perfusion scanning than in those receiving anticoagulation therapy(P
