Methotrexate vs.Gold Salt for Rheumatoid Arthritis:A Meta-analysis of Tolerance
- VernacularTitle:甲氨蝶呤与金制剂治疗类风湿性关节炎耐受性比较的Meta分析
- Author:
Fang ZHANG
;
Anjin CHEN
;
Ting FU
- Publication Type:Journal Article
- Keywords:
Methotrexate;
Gold salt;
Meta-analysis;
Rheumatoid arthritis
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the efficacy of methotrexate(MTX) vs.gold salt in treating patients with rheumatoid arthritis(RA).METHODS:7 studies on the efficacy of methotrexate(MTX) vs.gold salt in treating patients with rheumatoid arthritis(RA) were subjected to a meta-analysis using homogeneity test and combined effect test.RESULTS:Homogeneity test showed that the cited studies were homogeneous with ?2=25.14,df=6 and P=0.0003;and by combined test,the combined OR was 2.37(95% confidence interval=1.18～4.78,Z=2.41,P=0.02).CONCLUSION:Methotrexate demonstrated better toleration than gold salt for rheumatoid arthritis.
