6 Classes of Low-dosage of Antihypertensive Agents for Essential Hypertension
- VernacularTitle:6类降压药固定低剂量的单药降压疗效比较
- Author:
Congxiao HUA
;
Lu HUA
;
Na LI
;
Li WANG
;
Huimin PANG
;
Guanghua MING
;
Yan HUANG
;
Xiaoru CHENG
;
Hong LIU
;
Ying WU
;
Li XU
;
Jian KANG
;
Zhimin XU
;
Yishi LI
- Publication Type:Journal Article
- Keywords:
Essential hypertension;
Antihypertensive drug;
Monotherapy
- From:
China Pharmacy
2007;0(35):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To provide references for clinicians in the choice of antihypertensive drugs.METHODS:The antihypertensive efficacy 6 classes(or 15 kinds) of antihypertensive drugs in a monotherapy in the treatment of 370 patients with essential hypertension(EH) were compared.RESULTS:The blood pressure was effectively lowered by all of the antihypertensive drugs except doxazosin,and doxazosin and torasemide showed inferior efficacy in the reduction of diastolic blood pressure(DBP).CONCLUSION:Calcium antagonists with prolonged action,angiotensin converting enzyme inhibitor(ACEI),angiotens-in receptor antagonist,and the monotherapy of Terazosin or Indapamide can all effectively bring down the blood pressure.It is suggested that low-dose doxazosin and torasemide should not be used alone in treating essential hypertension.
