Preparation of Inclusion Compound of ?-carotene and Study on Its Stability
- VernacularTitle:?-胡萝卜素包合物的制备及稳定性研究
- Author:
Yehong ZHOU
;
Shaomin SHUANG
- Publication Type:Journal Article
- Keywords:
Cyclodextrin;
?-carotene;
Inclusion compound
- From:
China Pharmacy
2007;0(34):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare the inclusion compound of ?-carotene and study its stability. METHODS: Inclusion compound of ?-carotene with ?-CD was prepared by improved saturated water solution method. The stability of the inclusion compound was investigated by UV spectrophotometry and the content of ?-carotene was determined as well. RESULTS: In the inclusion compound, the content of ?-carotene was 5.54%. The stability of cyclodextrin complexed ?-carotene under heating, exposure to ultraviolet light and oxidizing agent was improved, and the remaining rate of ?-carotene increased by 34.4%, 1.8%, and 64.2%, respectively. CONCLUSION: The stability of ?-carotene was increased after encapsulation with ?-CD.