ADRs Induced by Saponins of Panax Notoginseng Injection:Literature Analysis of 81 Cases
- VernacularTitle:81例含三七总皂苷类注射剂致不良反应的文献分析
- Author:
Congyan ZENG
;
Quanxi MEI
- Publication Type:Journal Article
- Keywords:
Saponins of panax notoginseng;
Injection;
ADRs;
Literature;
Analysis
- From:
China Pharmacy
2007;0(33):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the general pattern and characteristics of the ADRs associated with Saponins of panax notoginseng(SPN)injection to guide rational administration of this drug.METHODS:ADR cases induced by SPN injection that retrieved from domestic medical journals between 1994 and 2006 were analyzed statistically.RESULTS:Of the total 81 ADR cases induced by SPN injection,females showing higher percentage than males,and the ADRs were more often seen in aged group.The ADRs usually occurred following second time injection or repeated injections.The clinical manifestations of ADRs varied and could involve multiple organs and systems,which were characterized predominantly by damages of skin and its appendages.CONCLUSION:Doctors and pharmacists should master the pattern and characteristics of ADRs and strengthen ADR monitoring so as to reduce the incidence of ADRs.
