Compound Azintamide Enteric-coated Tablet plus Mosapride Citrate Dispersible Tablet for Abdominal Distension in Patients with Functional Dyspepsia
- VernacularTitle:复方阿嗪米特肠溶片联合枸橼酸莫沙必利分散片治疗功能性消化不良腹胀
- Author:
Morong LIU
;
Haijun MU
;
Hongping LI
- Publication Type:Journal Article
- Keywords:
Compound azintamide;
Mosapride citrate dispersible tablets;
Functional dyspepsia;
Drug therapy
- From:
China Pharmacy
2007;0(32):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the efficacy of compound azintamide enteric-coated tablet plus mosapride citrate dispersible tablet for abdominal distention in patients with functional dyspepsia(FD).METHODS:A total of 80 patients with the chief complaint of abdominal distention were randomized to treatment group(Group A,n=40) to be treated with mosapride citrate dispersed tablets plus compound azintamide enteric-coated tablet,or control group in which the patients were treated bu mosapride citrate dispersed tablets(Group B,n=20) or compound azintamide enteric-coated tablets(Group C,n=20).Comp-ound azintamide enteric-coated tablets were administered orally tid(2 tablets) immediately after meal while the mosapride citrate dispersed tablets(5mg) were administered orally tid 30min before meal for 2 weeks.The main outcome measures were changes of symptom scores of abdominal distension,the total effective rates in improvement of abdominal distension,and drug side effects before and after treatment.RESULTS:After 1-week and 2-week treatment,the average index scores of abdominal distention in the treatment group(Group A) were significantly lower than in the control groups(Group B and Group C) (P
