Effect of Clozapine on Levels of Blood Glucose and Insulin in Patients with Schizophrenia
- VernacularTitle:氯氮平对精神分裂症患者血糖和胰岛素水平的影响
- Author:
Maorong CHEN
;
Huaifu WANG
;
Qiuhong CHEN
;
Rongsheng TONG
- Publication Type:Journal Article
- Keywords:
Clozapine;
Blood glucose;
Insulin level
- From:
China Pharmacy
2007;0(32):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the effects of clozapine on blood glucose and insulin levels in schizophrenic patients. METHODS:This is a self-controlled study in which the levels of blood glucose and insulin in clozapine group(n=63) were compared before and after treatment,and which were compared with the levels in the control group(n=64).Insular cellular antibody(ICA) and insulin autoantibody(IAA) were detected in patients with high level of blood glucose.RESULTS:After treatment for 8 weeks,the blood glucose level was increased in clozapine group as compared with the same group before treatment and the control group,showing significant differences(P
