Study of lymph node micrometastasis in thyroid carcinoma
- VernacularTitle:甲状腺癌淋巴结微转移的研究
- Author:
Xungeng LI
;
Hongyan MA
;
Xing JIN
- Publication Type:Journal Article
- Keywords:
Thyriod Neoplasms/pathol;
Lymphatic Micrometastasis;
MUC1
- From:
Chinese Journal of General Surgery
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the reliability and sensitivity of detection of thyroid carcinoma lymph node micrometastasis with MUC1.Methods In 488 cases of thyroid disease,1% methylene blue 1.0-2.0mL was injected into the thyroid nodule or surrounding thyroid tissue 24hours before operation.The dye-stained lymph nodes were detected at operation and RT-PCR method was used to determine MCUI in the clinically blue-stained lymph nodes.Results The detection rate of the blue-stained lymph nodes in thyroid carcinoma was 93%,and in benign lesions was 0%.In the research group,80 cases were found to have blue-stained lymph nodes,the detection rate was 95% and was higher than the pathologr diagnostic rate which was 86%(P
