Determination of the Titer of Azithromycin by Turbidimetric Method
- VernacularTitle:比浊法测定阿奇霉素效价的研究
- Author:
Kangjun WANG
- Publication Type:Journal Article
- Keywords:
Turbidimetry;
Azithromycin;
Titer determination;
Comparison
- From:
China Pharmacy
2007;0(31):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To develop a method for the determination of the titer of azithromycin. METHODS: Turbidimetric method was adopted to determine azithromycin and which was compared with cup-plate method. RESULTS: The linear range of azithromycin was 0.4~2.0IU?mL-1(r=0.999 1), with its recovery rate at 99.70%~100.02%(RSD=0.22%~0.46%), the determination results of 2 kinds of methods was no significant difference. CONCLUSION: Turbidimetric method was proved to be more rapid and convenient than the cup-plate method.