Preparation and Quality Control of Lornoxicam Gel
- VernacularTitle:氯诺昔康凝胶的制备及质量控制
- Author:
Wei WANG
;
Zuxiong LIU
;
Bei QIN
;
Qiang LI
- Publication Type:Journal Article
- Keywords:
Lornoxicam gel;
Preparation;
Quality control;
HPLC
- From:
China Pharmacy
2007;0(31):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To prepare lornoxicam chitosan gel and to study its quality control method. METHODS: Lornoxicam chitosan gel was prepared with chitosan as excipient. The content of lornoxicam was determined by HPLC. The stability of the preparation was studied by accelerated test and centrifugation. RESULTS: The prepared gel was well-spread, with linear range at 12.5～125.0?g?mL-1 and average recovery at 100.02%(RSD=1.18%). The indexes of stability all met the standard. CONCLUSION: The preparing technology of lornoxicam chitosan gel is simple, and its quality is stable reliable.
