Retrospective Analysis of Literature on Compatible Stability of Drugs Indexed in CHKD in 2005
- VernacularTitle:2005年中国医院知识仓库收载的药物配伍稳定性文章的调查分析
- Author:
Zhichang ZHENG
;
Rong TAN
- Publication Type:Journal Article
- Keywords:
CHKD;
Compatibility;
Stability;
Analysis
- From:
China Pharmacy
2007;0(31):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To probe into the overall situation about the study on compatible stability of drugs. METHODS: The compatible stability of drugs reported in a total of 113 articles in 2005 in 52 kinds of periodicals were retrieved from CHKD and summarized analytically. RESULTS: The drug categories involved were chiefly antibiotics (59%), Chinese traditional medicines or Chinese drug components (20%) and other drugs (21%). Quantitative analyses in 91 articles were chiefly conducted by ultraviolet spectrophotometry (79%) or HPLC (20%). CONCLUSION: Because the ultraviolet spectrophotometry was greatly used and some experimental designs were not well-knit enough, the reliability of experimental results of compatible stability of drugs might be seriously affected, which poses a great danger to the clinical compatible use of drugs.
