Quality Criteria of Huangzhi Oral Liquid
- VernacularTitle:黄蛭口服液质量标准研究
- Author:
Congyan ZENG
;
Quanxi MEI
;
Huifei WU
;
Yuqiao GAO
;
Xiwen ZHONG
- Publication Type:Journal Article
- Keywords:
Huangzhi oraL liquid;
TLC;
KjeLdahL determination;
HPLC;
Chrysophanol;
Quality criteria
- From:
China Pharmacy
2007;0(30):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the quality criteria for Huangzhi oral liquid.METHODS:TLC was employed to for the qualitative identificaiton of Radix et Rhizoma Rhei,Leech and Fructus Arctii;the content of total nitrogen was determined by KjeLdahL determination and content of Chrysophanol in Radix et Rhizoma Rhei in Huangzhi oral liquids was determined by HPLC.RESULTS:The TLC chromatograms of Radix et Rhizoma Rhei,Leech and Fructus Arctii presented the spots of the same colors with those at the corresponding places in the chromatograms of the controls.There was a good linear relationship within the concentration range of 1.696～ 8.480? g? mL-1 for Chrysophanol(r=0.999 8).The average recovery was 99.60%(RSD=1.37%,n=9).CONCLUSION:The methods are accurate and reliable with a strong specificity and can be used for the quality control of Huangzhi oral liquid.
