Diagnosis and surgical treatment of nonfunctioning pancreatic neuroendocrine carcinoma
- VernacularTitle:无功能胰腺神经内分泌癌的诊断与外科治疗
- Author:
Yi SHI
;
Yueming SUN
;
Yi MIAO
;
Menghua DAI
;
Quan LIAO
;
Yupei ZHAO
- Publication Type:Journal Article
- Keywords:
Pancreatic Neoplasms;
Carcinoma,Neuroendocrine/diag;
Carcinoma,Neuroendocrine /surg
- From:
Chinese Journal of General Surgery
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Positive expression of 2 or all 3 markers of neuroendocrine cell was detected in all 16 samples; negative expression of all 5 peptide hormones was observed in only 25% of samples. At a mean follow-up of 44.2 months (range 4 months-7 years ), the mean time from resection to relapse or metastasis was 29.8 months; 7 cases survived more than 5 years, of which 2 have survived for 7 years. Two cases, who subjected non-operative treatment, survired 39,61 months, respectively.Conclusions Clinical manifestations of NPNEC are non-specific. Only a few tumors in NPNEC patients do not yield peptide hormones. Treatment of NPNEC (including patients with liver metastasis) with aggressive surgical resection followed by interventional methods can result in excellent overall long-term survival.
