Improvement of Hydroscopicity of Traditional Chinese Drug Extractum by Spray Drying
- VernacularTitle:喷雾干燥法改善中药浸膏吸湿性的研究
- Author:
Zhi LI
;
Jing HAN
;
Qin CEN
;
Yuefeng PAN
;
Limei YIN
- Publication Type:Journal Article
- Keywords:
Spray drying;
Hydroscopicity;
Traditional Chinese drug extractum;
Improvement
- From:
China Pharmacy
2007;0(27):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To improve hydroscopicity and fluidity of traditional Chinese drug extractum by spray drying and to improve affixes to the wall of the drier during drying for providing reasonable relative humidity of production.METHODS:The compounding of adjuvant and the technology were optimized by orthogonal experiment,and the hydroscopicity and fluidity of powdered extract were investigated.RESULTS:The hydroscopicity of traditional Chinese drug extractum can be greatly decreased by adding 3% gum arabic and 7% ?-CD.The optimum technological conditions were as follows:extractum density of 1.10g? mL-1,temperature of intake airflow of 170℃,atomization pressure of 0.5Mpa,and feed material speed of 400mL? h-1 by orthogonal experiment.The critical relative humidity of the optimum formula was 64%.CONCLUTION:The problems of time consuming and moisture absorption of traditional Chinese drug extractum existed in the traditional old technology can be improved in this new technology.
