Serine protease HtrA2/Omi and cell death or survival
- VernacularTitle:丝氨酸蛋白酶HtrA2/Omi与细胞存亡
- Author:
Huan DENG
;
Liangming LIU
;
Jixiang ZHANG
- Publication Type:Journal Article
- Keywords:
HtrA2/Omi;
Mitochondria;
Apoptosis
- From:
Chinese Journal of Pathophysiology
1999;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
The serine protease HtrA2/Omi is released from the mitochondrial intermembrane space following apoptotic stimuli.Once in the cytosol,HtrA2/Omi has been implicated in promoting cell death in caspase-dependent or caspase-independent pathway.On the other hand,HtrA2/Omi can refold and degrade misfolded proteins in the mitochondria during cell stress.
