A 1:1 Matched Case-control Study on Factors of Alzheimer’s Disease
- VernacularTitle:阿尔茨海默病相关因素1:1配对病例-对照研究
- Author:
Yuling ZHANG
;
Helang HUANG
;
Yisheng ZHOU
- Publication Type:Journal Article
- Keywords:
Alzheimer’s disease;
Case-control study;
Conditional logistic regression
- From:
Chinese Journal of Prevention and Control of Chronic Diseases
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the factors of Alzheimer’s Disease (AD). Methods A 1:1 matched case-control study was conducted. The study included 129 patients of clinically diagnosed AD and 129 controls selected from Nanchang and Jiujiang areas. The data were analyzed by the conditional logistic regression. Results The results showed the unsociable personality (OR=2.486,95%CI=1.075～6.638),the history of great negative life events (OR=4.125,95%CI=1.706～12.249),using cookers made of aluminum (OR=2.454,95%CI=1.277～5.268) were identified as risk factors for AD. The good family income state (OR=0.324,95%CI=0.106～0.828) and frequently physical exercises (OR=0.258,95%CI=0.104～0.520) were protective factors for AD. Conclusion Alzheimer’s Disease seems to be related to the income state,frequency of physical exercises,personality,big negative life events,using cookers made of Aluminum.
