The perioperative management of orthotopic liver transplantation in Chinese inbred miniature porcine
- VernacularTitle:小型猪非转流原位肝移植的围手术期处理
- Author:
Mingxin PAN
;
Fandong KONG
;
Aihui LI
;
Jinmin XIE
;
Yi ZHANG
;
Ling WANG
;
Yi GAO
- Publication Type:Journal Article
- Keywords:
Liver Transplantation/methods;
Perioperative Management;
Inbred Miniature Porcine
- From:
Chinese Journal of General Surgery
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarise the perioperative features of orthotopic liver transplantations(OLTs) in miniature porcine,to establish mature、stable OLT models.Methods In order to observe hemodynamics and blood changes and improved perioperative management and summarise the perioperative characteristics,8 preliminary experiments(group A) and 18 experiments(group B) of OLTs were performed without veno-venous bypass(VVB) in Chinese inbred miniature porcine.Results The mean operation time was(179.6?14.3)min in our 18 OLTs,and the mean anhepatic phase time was(27.3?3.4)min.Dramatic hemodynamic and metabolic changes were identified during anhepatic phase.The oneweek survival rate was 88.9% in group B,but all the 8 pigs in group A died.The experiment group pigs urinated after 3～5hours and had normal diet after 3days.Conclusions Decreasing the operation time and stability of hemodynamics in anhepatic phase are the keys for success in OLTs without VVB.
