The value of BCSG1 on evaluating the curative effect of neoadjuvant chemotherapy for breast cancer
- VernacularTitle:BCSG1基因在乳腺癌新辅助化疗疗效评估中的价值
- Author:
Jinsong HE
;
Jianhui YUAN
;
Xianming WANG
;
Liangfeng GUO
;
Guoxian ZHU
;
Jianchun WU
;
Rong LI
;
Min WANG
;
Weicai CHEN
;
Huisheng WU
- Publication Type:Journal Article
- Keywords:
Breast Neoplasms;
BCSG1;
Neoadjuvant Chemotherapy
- From:
Chinese Journal of General Surgery
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of BCSG1 on evaluating the curative effect of neoadjuvant chemotherapy(NC) for breast cancer.Methods The expression of BCSG1 in cancer tissue was assayed by immunohistochemistry and RT-PCR in 36 cases of breast cancer patients before and after receiving NC of CEF(cyclophosphamide,epirubicin and fluorouracil) regimen.The therapeutic response of NC was evaluated by morphological and pathological observation.The relationship between expression of BCSG1 and morphological response to NC was analyzed.Results Among the studied cases,the diameter of tumor significantly decreased(P
