Effect of rhGH on the Protein Expression of NF-?B P65 in Ischemic Reperfusion Injury of Rat Liver
- VernacularTitle:rhGH对大鼠肝脏缺血再灌注损伤中NF-?B P65蛋白表达的影响
- Author:
Jianghua RAN
;
Yongzhang GUO
;
Li LI
;
Shengning ZHANG
;
Zhu LI
;
Jing LIU
- Publication Type:Journal Article
- Keywords:
Recombinant human growth hormone;
Ischemic reperfusion injury;
Nuclear factor kappa B P65
- From:
Journal of Kunming Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of recombinant human growth hormone(rhGH)on the protein expression of NF-?B P65 in ischemic reperfusion injury of rat liver.Methods One hundred male rats models were constructed by Pringle's method and were randomly divided into two groups: the rhGH group and the control group.In rhGH group, the rats were injected(0.2IU/100g weight)seven days before the ischemic reperfusion injury,while in control group,rats was replaced by normal sodium.The levels of protein expression of NF-?B P65 were detected by Western blotting and immunohistochemistry.Results Compared with control group,the expression of NF-?B P65 and NF-?B activity(P
